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Education Track Sessions

  • Sterile Compounding
  • Monday  |  
  • 4/20/2026  |  
  • 5:30 PM – 
  • 6:30 PM
  •   |  Room: Cottonwood 6-7

Admixing Alchemy: Stability and Compatibility Considerations for Home Parenteral Nutrition

Parenteral nutrition (PN) is one of the most complex drug prescriptions available, containing from 20 – 40 ingredients (Boullata 2014), and is defined by the Institute for Safe Medication Practices (ISMP) as a high-alert medication, meaning a medication that may heighten the risk of significant patient harm (Rich et al, 2013). Due to the large number of additives in PN, PN solutions are at risk for incompatibility and instability, and these considerations, along with sterility considerations, are imperative for determining beyond-use-dating of PN. In this session, we will review considerations for compatibility and stability of PN solutions and discuss how these considerations can be applied to prescribing, compounding, storing, and administering HPN.
Parenteral nutrition (PN) is one of the most complex drug prescriptions available, containing from 20 – 40 ingredients (Boullata 2014), and is defined by the Institute for Safe Medication Practices (ISMP) as a high-alert medication, meaning a medication that may heighten the risk of significant patient harm (Rich et al, 2013). Due to the large number of additives in PN, PN solutions are at risk for incompatibility and instability, and these considerations, along with sterility considerations, are imperative for determining beyond-use-dating of PN. In this session, we will review considerations for compatibility and stability of PN solutions and discuss how these considerations can be applied to prescribing, compounding, storing, and administering HPN.

Learning Objectives

  • Provide overview of stability and compatibility of parenteral nutrition (PN).
  • Identify adverse events associated with instability and incompatibility of PN solutions.
  • Review ASPEN guidelines regarding stability and compatibility of PN solutions.
  • Identify common barriers to implementing stability and compatibility information in practice and describe strategies to overcome these challenges.
  • Explain how the interdisciplinary team plays a role in the PN compounding process.

    • Speaker(s)

    Adina Hirsch PharmD, BCNSP, FASPEN Senior Medical Science Liaison, Medical Affairs, Parenteral Nutrition
    Fresenius Kabi

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    Speaker
    Adina Hirsch PharmD, BCNSP, FASPEN
    Senior Medical Science Liaison, Medical Affairs, Parenteral Nutrition
    Fresenius Kabi

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    Registration for the Sterile Compounding Clinic Required