California’s updated sterile compounding regulations represent a significant shift in how pharmacies approach compliance, training, documentation, and quality assurance. With the repeal of previous compounding sections and the introduction of new regulatory articles addressing sterile compounding, pharmacies must reassess policies, workflows, and competency programs to ensure alignment with the updated requirements. This roundtable discussion will explore the practical implications of Article 4.6 (Section 1736) on sterile compounding, including new expectations for personnel training and competency documentation, expanded labeling and recordkeeping requirements, quality assurance procedures, and updated standards for cleaning and environmental control.