Successful onboarding is critical to nurse confidence, retention, and patient safety—especially in the highly specialized home infusion setting. This interactive roundtable will bring together nursing leaders, educators, and operational stakeholders to explore what a strong, scalable onboarding program for home infusion nurses should look like. Discussion will focus on essential onboarding components, including core clinical and operational competencies, effective preceptor and mentor models, and practical approaches to tracking onboarding progress and annual competency completion. Participants will also examine real-world challenges that impact onboarding success.